Research Article

The Protective Effect of Beraprost Sodium on Diabetic Nephropathy by Inhibiting Inflammation and p38 MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats

Table 6

Immunohistochemical expression of CD31 and collagen type IV in kidney tissues of rats in experiment (, ).

Integrated optical density (IOD)CN groupT2DM groupBPS group

CD312546.83 ± 253.057485.00 ± 289.745467.50 ± 422.93
Collagen type IV2283.67 ± 554.558418.00 ± 738.007185.50 ± 482.97

and T2DM group and BPS group compared with CN group rats and and BPS group compared with the T2DM group.