Papillary Thyroid Carcinoma Arising in Children and Adolescent Hashimoto’s Thyroiditis: Ultrasonographic and Pathologic Findings

Table 1

Clinical and ultrasonographic, pathologic features of patients with papillary thyroid carcinoma.

Case

Age/sex

Site

US findings

FNA or core biopsy

Op

Op pathology

Diffuse calcifications on pathology

Diffuse sclerosing variant

Lymphocytic thyroiditis

Extrathyroidal extension

Type of calcifications on pathology

Rt neck nodes

Lt neck nodes

1

12/F

Both

Diffuse calcifications

Suspicious for PTC (FNA)

TT with both RND

PTC

Yes

No

Yes

Yes

Psammomatous

II–IV, VI

II–IV, VI

2

12/F

Lt

Diffuse calcifications

Follicular cell lesion, indeterminate (FNA)

TT with left RND

PTC

Yes

Yes

Yes

Yes

Psammomatous

No

II, III, VI

3

13/F

Both

Diffuse calcifications

PTC (core-biopsy)

TT with both RND

PTC

Yes

Yes

Yes

Yes (with thymic metastasis)

Psammomatous

II–IV, VI

II–IV, VI

4

18/F

Both

Diffuse calcifications

PTC (FNA)

TT with both RND

PTC

Yes

Yes

Yes

Yes (Microscopic extension)

Psammomatous

II, III

II–IV, VI, delphian node

5

18/F

Rt

Mass with internal calcifications

PTC (FNA)

TT with right RND

PTC

Yes

No

Yes

Yes

Psammomatous

II–IV, VI

N/A

6

6/F

Both

Oval well defined hypoechoic mass with calcifications

Suspicious for PTC (FNA)

TT with both RND

PTC

Yes

No

No

Yes

Psammomatous

II–IV, VI

II–IV, VI

7

18/M

Lt

Oval ill-defined isoechoic mass with calcifications

Suspicious for PTC (FNA)

TT with left RND

PTC

Yes

No

No

Yes

Psammomatous

No

II–IV

8

19/F

Rt

Taller than wide hypoechoic mass with calcifications

PTC (FNA)

TT with right RND

PTC

No

No

No

No

No

V, VI

No

9

17/M

Lt

N/A

Follicular cell lesion (FNA)

Lt thyroidectomy

PTC

No

No

No

No

Psammomatous

No

No

10

18/F

Rt

N/A

PTC (FNA)

TT with right RND

PTC

No

No

Yes

Yes

Dystrophic

II–VI

No

11

19/F

Rt

Mass with calcifications

PTC (FNA)

TT with right RND

PTC

No

No

Yes

Yes; (Microscopic extension)

Psammomatous

II–IV, VI

No

US: ultrasonography; Op: operation or type of surgery; Rt: right; Lt: left; FNA: fine needle aspiration; PTC: papillary thyroid carcinoma; TT: total thyroidectomy; RND: radical neck dissection; N/A: not applicable.