Research Article
Alteration of Thyroid-Related Hormones within Normal Ranges and Early Functional Outcomes in Patients with Acute Ischemic Stroke
Table 1
Baseline characteristics of patients with acute ischemic stroke.
| | Clinical variables | | | Age (years) (median, IQR) | 67 (59–76) | | Sex (male, %) | 441 (61.1%) | | Smoking (, %) | 300 (41.6%) | | Hyperlipidemia (, %) | 296 (41.0%) | | Coronary artery disease (, %) | 56 (7.8%) | | Diabetes mellitus (, %) | 176 (24.4%) | | Atrial fibrillation (, %) | 55 (7.6%) | | Previous stroke (, %) | 84 (11.6%) | | Transient ischemic attacks (, %) | 23 (3.2%) | | History of hypertension (, %) | 479 (66.3%) |
| | Blood pressure on admission (median, IQR) | | | Systolic blood pressure (mmHg) | 158 (140–174) | | Diastolic blood pressure (mmHg) | 82 (74–92) | | Baseline NIHSS scores (median, IQR) | 2 (1–4) | | Mild severity at admission (NIHSS < 8) (, %) | 627 (86.8%) |
| | Laboratory variables (median, IQR) | | | TSH (IU/L) | 1.6 (1.1–2.3) | | Total T4 (µg/dL) | 6.6 (5.8–7.5) | | Total T3 (ng/mL) | 0.8 (0.7–1.0) | | Free T4 (ng/dL) | 1.1 (1.0–1.2) | | Free T3 (pg/mL) | 2.5 (2.3–2.8) | | Initial WBC count (×109/L) | 6.9 (5.7–8.6) | | Glucose on admission (mmol/L) | 7.1 (5.8–9.4) | | C-reactive protein (mg/dL) | 1.9 (0.9–4.1) | | Poor functional outcome (mRS > 2) (, %) | 85 (11.8%) |
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IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; TSH, thyroid-stimulating hormone; T4, thyroxine; T3, triiodothyronine; WBC, white blood cell; mRS, modified Rankin Scale.
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