Alteration of Thyroid-Related Hormones within Normal Ranges and Early Functional Outcomes in Patients with Acute Ischemic Stroke

Table 3

Admission clinical and laboratory findings according to outcome.

	Good functional outcome (mRS ≤ 2) ()	Poor functional outcome (mRS > 2) ()
Systolic blood pressure (mmHg)	157.4 ± 25.0	156.7 ± 22.0	0.813
Diastolic blood pressure (mmHg)	83.2 ± 13.8	83.8 ± 15.1	0.724
Baseline NIHSS scores (median, IQR)	2.0 (1–3)	10 (7–13)	0.000
TSH (IU/L) (median, IQR)	1.6 (1.06–2.27)	1.56 (1.06–2.12)	0.429
Total T3 (ng/mL) (median, IQR)	0.84 (0.74–0.95)	0.79 (0.63–0.89)	0.001
Total T4 (µg/dL) (median, IQR)	6.48 (5.74–7.42)	7.13 (6.08–8.07)	0.001
Free T3 (pg/mL) (median, IQR)	2.54 (2.29–2.85)	2.39 (2.12–2.66)	0.000
Free T4 (ng/dL) (median, IQR)	1.08 (0.99–1.19)	1.13 (1.03–1.26)	0.001
Free T3/free T4 (median, IQR)	2.36 (2.08–2.68)	2.08 (1.85–2.37)	0.000
Initial WBC count (×10^9/L) (median, IQR)	6.8 (5.6–8.6)	7.9 (6.3–9.3)	0.722
Glucose on admission (mmol/L) (median, IQR)	7.0 (5.8–9.3)	7.6 (6.0–11.4)	0.122
C-reactive protein (mg/dL) (median, IQR)	1.8 (0.9–4.1)	2.4 (1.0–4.7)	0.025

mRS, modified Rankin Scale; IQR, interquartile range; TSH, thyroid-stimulating hormone; T3, triiodothyronine; T4, thyroxine; WBC, white blood cell.