Review Article
Robotic versus Open Thyroidectomy for Differentiated Thyroid Cancer: An Evidence-Based Review
Table 1
Summary of recurrent laryngeal nerve injury in published studies.
| First author/year | RT approach | Sample size (RT versus OT) | Definition of transient RLN injury | Rates of transient RLN injury (%) (RT versus OT) | Definition of permanent RLN injury | Rates of permanent RLN injury (%) (RT versus OT) |
| Lee, 2013 [22] | TA | 62 : 66 | Not stated | 3.2 : 4.5 ( = 0.21) | Not stated | 0 : 0 ( = NS) |
| Ryu, 2013 [23] | TA | 45 : 45 | — | NR | Not stated | 0 : 0 ( = NS) |
| Tae, 2012 [24] | GUAB | 75 : 226 | Vocal cord palsy on laryngoscopy with recovery within 6 months | 8.0 : 3.1 ( = 0.09) | Vocal cord palsy on laryngoscopy failed to recover after 6 months | 0 : 0.4 ( = 1.0) |
| Lee, 2012 [25] | TA | 192 : 266 | Not stated | 2.6 : 0.4 ( = 0.08) | Not stated | 6.8 : 0 ( = 0.07) |
| Kang, 2012 [26] | TA | 56 : 109 | Not stated | 3.6 : 2.8 ( = 0.77) | Not stated | 0 : 0 ( = NS) |
| Lee, 2010 [27] | TA | 41 : 43 | Vocal cord palsy on laryngoscopy with recovery within 6 months | 2.4 : 0 ( = NS) | Vocal cord palsy on laryngoscopy not recovered after 6 months | 0 : 0 ( = NS) |
| Tae, 2011 [28] | GUAB | 41 : 163 | Not stated | 2.4 : 2.5 ( = 0.73) | Not stated | 0 : 0.6 ( = 0.79) |
| Kim, 2011 [29] | BABA | 69 : 138 | Vocal cord palsy on laryngoscopy not recovering within 6 months | 1.4 : 0.7 ( = 0.62) | Failure of voice change to normalize after 6 months | 0 : 0 ( = NS) |
| Yi, 2013 [30] | TA | 98 : 423 | Not stated | 1.0 : 0.5 ( = 0.46) | — | NR |
| Kim, 2015 [31] | BABA | 13 : 65 | Vocal cord palsy on laryngoscopy lasting for <6 months | 0 : 4.6 ( = NS) | Vocal cord palsy on laryngoscopy lasting for >6 months | 0 : 3.1 ( = NS) |
| Kwak, 2015 [32] | BABA | 206 : 634 | Vocal cord palsy on stroboscopy from 2 weeks to 6 months | 0.9 : 0.5 ( = 0.36) | — | NR |
| Noureldine, 2013 [33] | TA | 24 : 35 | Vocal cord palsy on laryngoscopy lasting for <6 months | 4.1 : 5.7 ( = 0.76) | Vocal cord palsy on laryngoscopy persisting after 6 months | 0 : 0 ( = NS) |
| Lee, 2014 [34] | TA | 60 : 56 | Not stated | 5.0 : 0 ( = 0.24) | — | NR |
| Tae, 2014 [35] | GUAB | 62 : 183 | Not stated | 6.5 : 2.2 ( = 0.11) | Not stated | 0 : 0 ( = NS) |
| Lee, 2014 [36] | TA | 43 : 51 | Not stated | 2.3 : 0 ( = 0.45) | — | NR |
| Kim, 2014 [37] | BABA | 123 : 392 | Vocal cord palsy persisted <6 months | 4.9 : 6.1 ( = 0.60) | Vocal cord palsy persisted >6 months | 0 : 0.3 ( = 1.0) |
| Song, 2014 [38] | GUAB | 118 : 176 | Not stated | 0.8 : 2.8 ( = 0.40) | Not stated | 0 : 0 ( = NS) |
| Lee, 2012 [39] | TA | 42 : 46 | Vocal fold motion impairment on videolaryngostroboscopy from 1 week to 3 months | 21.4 : 19.5 ( = 0.82) | — | NR |
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RT, robotic thyroidectomy; OT, open thyroidectomy; RLN, recurrent laryngeal nerve; TA, transaxillary approach; GUAB, gasless unilateral axillobreast approach; BABA, bilateral axillobreast approach; , value; NS, nonsignificant; NR, not reported.
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