Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus

Table 1

Clinical, laboratory, and thyroid ultrasonography characteristics of study subjects ().

Variables	Thyroid nodule group ()	Control group ()	or χ^2 values	values
Male (n (%))	102 (50.7)	224 (72.7)	25.521	<0.001
Age (years)	59.13 ± 10.23	52.3 ± 11.23	6.930	<0.001
BMI (kg/m^2)	26.69 ± 3.64	26.60 ± 3.96	0.245	0.806
WC (cm)	95.81 ± 8.13	96.01 ± 8.41	−2.66	0.790
FBG (mmol/L)	8.63 ± 3.09	8.26 ± 1.96	1.661	0.097
HbA1C (%)	9.04 ± 2.04	9.33 ± 2.13	−1.576	0.116
ALT (IU/L)	21.80 ± 12.42	24.14 ± 16.34	−1.73	0.084
AST (IU/L)	18.59 ± 7.18	19.65 ± 9.59	−1.346	0.179
BUN (mmol/L)	5.45 ± 1.73	5.27 ± 1.61	1.251	0.212
Scr (μmol/L)	63.86 ± 21.42	62.30 ± 15.77	0.947	0.344
UA (μmol/L)	291.61 ± 81.94	294.26 ± 93.46	−0.328	0.743
TG (mmol/L)	2.17 ± 3.06	2.09 ± 2.07	0.378	0.706
TC (mmol/L)	4.82 ± 1.33	4.66 ± 1.19	1.424	0.155
FINS (mIU/L)	18.22 ± 9.39	13.95 ± 11.40	4.425	<0.001
HOMA-IR	8.2 ± 7.65	6.31 ± 9.25	0.159	0.016
TSH (μIU/mL)	2.17 ± 1.00	2.08 ± 0.92	1.082	0.28
FT3 (pmol/L)	4.46 ± 0.53	4.57 ± 0.61	−1.981	0.048
FT4 (pmol/L)	17.04 ± 2.09	16.59 ± 2.11	2.363	0.019
TPOAb (IU/mL)	8.2 ± 7.65	6.31 ± 9.25	−0.8	0.424
Thyroid nodule volume (mL)	0.29 ± 0.53	—	—	—
Thyroid nodule size (cm)	0.82 ± 0.45	—	—	—

Values are expressed as mean ± SD or n (%). BMI: body mass index; WC: waist circumference; FBG: fasting blood glucose; HbA1c: glycated hemoglobin typeA1c; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; Cr: creatinine; UA: uric acid; TG: triglyceride; TC: total cholesterol; FINS: fasting insulin; HOMA-IR: homeostasis model assessment insulin resistance; TSH: thyroid stimulating hormone; FT4: free thyroxine; FT3: free triiodothyronine; TPO: thyroid peroxidase antibody.