Research Article
Increased Chromosomal and Oxidative DNA Damage in Patients with Multinodular Goiter and Their Association with Cancer
Table 2
CBMN-cyt assay parameters and plasma 8-OHdG levels in patients with multinodular goiter and control subjects (mean ± SD).
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BN cells: binucleated cells; MN: micronucleus; NPBs: nucleoplasmic bridges; NBUDs: nuclear buds; 8-OHdG: 8-hydroxy-2′-deoxyguanosine; and SD: standard deviation. NDI = [1 + 2(2) + 3(3) + 4(4)]/, where 1–4 represent the total number of lymphocytes with one to four nuclei scored on 1000 viable cells (excluding necrotic and apoptotic cells; : the number of nuclei; : the total number of viable cells scored). |