Distribution of Adiponectin Receptors 1 and 2 in the Rat Olfactory Bulb and the Effect of Adiponectin Injection on Insulin Receptor Expression

Figure 1

Presence and distribution of AdipoR1 in OB tissue from intact rats. Schematic representation of anatomical localization of the main OB layers (scheme modified from [28]) (a). As it is observed, AdipoR1 immunoreactivity is found in periglomerular (b), mitral (c), and granular cell layers (d). Double immunostaining shows that AdipoR1 colocalize with both neuronal marker (b and d, arrow) and astrocyte marker (e, arrowhead). Interestingly, mitral cells do not stain with NeuN marker. Nuclei were counterstained with DAPI to identify the different layers of OB. Scale bar corresponds to 20 μm (40X). GloL: periglomerular cell layer; MitL: mitral cell layer; and GraL: granular cell layer.