Factors Associated with the Prevalence of Thyroid Nodules and Goiter in Middle-Aged Euthyroid Subjects

Table 2

Relationship between thyroid volume and different variables in subjects with and without thyroid nodules.

Characteristic	Thyroid volume
	Nodular thyroid		Nonnodular thyroid
	ρ	value	ρ	value
TSH (mU/L)	−0.43	<0.001	−0.17	0.012
FT4 (pmol/L)	0.12	0.252	0.11	0.099
ATPO (kU/L)	−0.05	0.613	0.02	0.75
Insulin (mU/L)	0.14	0.171	0.21	0.002
FPG (mmol/L)	0.22	0.03	0.27	<0.001
HOMA-IR	0.17	0.086	0.26	<0.001
Leptin (pg/L)	−0.29	0.004	−0.12	0.083
TC (mmol/L)	0.02	0.83	−0.02	0.742
HDL (mmol/L)	−0.3	0.003	−0.37	<0.001
LDL (mmol/L)	0.11	0.275	0.13	0.062
TG (mmol/L)	0.12	0.238	0.24	<0.001
SBP (mmHg)	0.19	0.066	0.14	0.037
DBP (mmHg)	0.29	0.004	0.14	0.036
WC (cm)	0.33	0.001	0.41	<0.001
BMI (kg/m^2)	0.22	0.026	0.3	<0.001
Smoking	0.3	0.003	0.21	0.001

ATPO: antithyroid peroxidase antibodies; BMI: body mass index; DBP: diastolic blood pressure; FPG: fasting plasma glucose; FT4: free thyroxine; HDL: high-density lipoprotein; HOMA-IR: insulin resistance index; LDL: low-density lipoprotein; SBP: systolic blood pressure; TC: total cholesterol; TG: triglycerides; TSH: thyroid-stimulating hormone; WC: waist circumference; ρ: correlation coefficient.