Thyroid Cancer in Saudi Arabia: A Histopathological and Outcome Study

Table 5

Univariate and multivariate analyses of demographic and histopathological predictive factors for the outcome at the last follow-up visit.

Outcome at final follow-up
Unadjusted				Adjusted
Characteristic	Remission	Persistent/recurrent disease	value	Odds ratio (95% CI)	value
Male gender	52/318 (16.4%)	80/225 (31.4%)	<0.0001	1.48 (0.64–3.4)	0.36
Age at diagnosis (yrs)	36.7 ± 12.9	43.5 ± 15.6	<0.0001	1.039 (1.012–1.07)	0.005
Tumor size (cm)	3.3 ± 2.3	3.4 ± 2.4	0.84
Tumor multifocality	143/272 (52.6%)	92/186 (49.5%)	0.58
Extrathyroidal extension	85/258 (32.9%)	115/199 (57.8%)	<0001	3.26 (1.43–7.42)	0.005
Lymphovascular invasion	29/110 (26.4%)	39/77 (50.6%)	0.001	1.52 (0.69–3.34)	0.30
Lymph node metastasis	128/313 (40.9%)	143/248 (57.7%)	<0.0001	1.11 (0.51–2.43)	0.79
Distant metastasis	19/316 (6%)	55/248 (22.2%)	<0.0001	2.11 (0.77–5.78)	0.15