More Favorable Metabolic Impact of Three-Times-Weekly versus Daily Growth Hormone Treatment in Naïve GH-Deficient Children

Table 2

Difference in metabolic parameters between patients grouped according to the GH treatment regimen (group A and group B) at baseline.

	7 doses per week; (group A) 16 patients	3 doses per week; (group B) 16 patients
	Mean ± SD	Mean ± SD	p
Fasting glucose (mmol/L)	4 ± 0.65	4.17 ± 0.45	0.801
Fasting insulin (IU/mL)	2.9 ± 2.2	2.8 ± 2.2	0.687
HbA1c (%)	5.1 ± 0.3	5.3 ± 0.3	0.108
Homa-IR	0.52 ± 0.41	0.53 ± 0.41	0.688
ISI-Matsuda	9.65 ± 0.82	9.03 ± 1.63	0.186
DIo	4.48 ± 1.81	4.68 ± 1.39	0.548
Total cholesterol (mmol/L)	4.12 ± 0.76	3.98 ± 0.51	0.130
HDL cholesterol (mmol/L)	1.58 ± 0.44	1.65 ± 0.31	0.563
LDL cholesterol (mmol/L)	2.84 ± 0.53	2.11 ± 0.36	0.063
Triglycerides (mmol/L)	1.50 ± 0.41	1.38 ± 0.52	0.942

BMI: body mass index; DIo: oral disposition index.