GH, IGF-1, and Age Are Important Contributors to Thyroid Abnormalities in Patients with Acromegaly

Figure 1

(a) Comparisons of thyroid volume in the groups divided by the median nadir GH, random GH, and IGF-1. value < 0.05; value < 0.01. (b) Comparisons of the GH burden and the age of diagnosis between the groups of patients with and without thyroid abnormalities. value < 0.05; value < 0.01. (c) Nucleotide sequencing result showing wild-type BRAF (indicated by an arrow) in the specimens of the pituitary adenoma of the patient with thyroid cancer. (d) Nucleotide sequencing result showing the T to A missense point mutation (indicated by an arrow) in the PTC of the patient with thyroid cancer.

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