Immunohistochemical Study of NR2C2, BTG2, TBX19, and CDK2 Expression in 31 Paired Primary/Recurrent Nonfunctioning Pituitary Adenomas

Table 1

Characteristics of the cohort.

	Noninvasion; N=41	Invasion; N=19	P	Nonrecurrence N=60	Recurrence; N=43	P	Paired-recurrence; N =31
Age	52.00±10.20	54.05±11.34	0.488	52.65±10.54	40.84±12.93	<0.001	37.48±11.58
Sex (M/F)	25/16	6/13	0.034	31/29	14/29	0.054	11/20
Volume	3591 (1680-6292)	8120 (5288-12818)	<0.001	4885 (2078-8085)	7936 (5240-14548)	0.001	10140 (6125-14548)
Maximum diameter	22.83±5.73	32.00±9.64	0.001	25.73±8.31	31.05±9.69	0.004	31.94±9.73
Invasion (N/Y)	-	-	-	41/19	17/26	0.004	12/19
Follow-up time	44.41±17.93	37.26±16.98	0.150	42.15±17.81	31.81±16.04	0.003	31.65±15.80