Research Article
Transcriptome Analysis Reveals Significant Differences in Gene Expression of Malignant Pheochromocytoma or Paraganglioma
Table 1
Clinical demographics of malignant and benign PC/PG cases obtained from the TCGA database and the COMETE cohort.
| Characteristic | Malignant (n = 30) | Benign (n = 199) | p value |
| Age (years), mean ± SD | 38.9 ± 14.4 | 43.2 ± 15.7 | 0.140 | Gender, n (%) | 30 | 199 | 0.432 | Male | 15 (50.0) | 83 (51.1) | | Female | 15 (50.0) | 116 (48.9) | | Race, n (%) | 11 | 46 | 0.497 | White | 10 (90.9) | 36 (78.2) | | African-American | 1 (9.1) | 5 (10.9) | | Asia | 0 (0) | 5 (10.9) | | Laterality, n (%) | 6 | 41 | 0.749 | Right | 2 (33.3) | 19 (46.4) | | Left | 4 (66.7) | 21 (51.2) | | Bilaterality | 0 (0) | 1 (2.4) | | Diagnosis, n (%) | 30 | 199 | <0.001 | PC | 15 (50.0) | 177 (87.2) | | PG | 15 (50.0) | 22 (12.8) | | Size (mm), mean ± SD | 73.4 ± 28.1 | 46.8 ± 20.2 | <0.001 | Follow-up (days), mean ± SD | 2460.2 ± 2658.9 | 1617.6 ± 867.7 | 0.320 |
|
|
PC: pheochromocytoma; PG: paraganglioma.
|