Transcriptome Analysis Reveals Significant Differences in Gene Expression of Malignant Pheochromocytoma or Paraganglioma
Table 3
Ingenuity Canonical Pathways and the corresponding genes in the transcriptome analysis differentiating malignant PC/PG cases in TCGA and COMETE cohort.
Ingenuity Canonical Pathways
Regulation
Up
Down
Cyclins and Cell Cycle Regulation
CCNA2, CDK1
Dopamine-DARPP32 Feedback in cAMP Signaling
PRKACB
Mitotic Roles of Polo-Like Kinase
CDK1, ESPL1
Cell Cycle Control of Chromosomal Replication
CDK1, CDT1, TOP2A
Cardiac β-adrenergic Signaling
PRKACB
Dopamine Receptor Signaling
PRKACB
Role of CHK Proteins in Cell Cycle Checkpoint Control
CDK1
Pyrimidine Deoxyribonucleotides De Novo Biosynthesis I
