Type 2 Diabetes and Cardiovascular Risk in Women
1Dipartimento di Medicina Clinica e Sperimentale, Policlinico Universitario “G. Martino,” Via C. Valeria, 98121 Messina, Italy
2Cattedra di Medicina di Genere, Università di Padova, Direttore U.O.C. di Medicina Generale, Azienda Ospedaliera di Padova, Via Giustiniani, 235128 Padua, Italy
3Dipartimento di Farmacologia Clinica ed Epidemiologia, Fondazione Mario Negri Sud, Centro Studi e Ricerche AMD, Via Nazionale 8/A, Santa Maria Imbaro, Italy
4Division of Endocrinology and Metabolism Department of Internal Medicine III, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria
Type 2 Diabetes and Cardiovascular Risk in Women
Description
Cardiovascular diseases (CVDs) are the leading cause of death, also in women. Women generally have a ~10-year delay in the onset of cardiovascular events as compared to men; however, diabetes seems to eliminate this “gender advantage,” with diabetic women showing even a higher risk for coronary heart disease (CHD) than diabetic men. Furthermore, diabetic women are more unlikely to achieve a good metabolic control than men and, overall, show a worse CVD risk profile. These sex discrepancies in terms of diabetes-related CVD complications have attracted the interest of clinicians and researchers, since they are not entirely attributable to a diverse prevalence of CVD risk factors or to different therapeutic strategies.
Thus, beyond chronic hyperglycaemia, a number of other factors such as dyslipidemia, hypertension, hormonal, genetic and environmental factors, and low-grade systemic inflammation and endothelial damage may contribute with a different impact to the atherosclerosis process associated with diabetes in women. Many of these factors show gender differences in their prevalence and /or association with CVD events.
We invite investigators to submit original research as well as review articles aimed to explore the peculiarity of CVD in women with type 2 diabetes. Potential topics include, but are not limited to:
- CVD risk definition in the clinical practice
- Role of atherogenic dyslipidemia, exploring “quantitative” and “qualitative” alterations of lipid pattern in diabetic women
- Contribution of menopause in CVD risk definition
- Diabetic nephropathy and CVD in diabetic women
- Differences in treatments and personalized therapeutic strategies
- Chronic inflammation and endothelial dysfunction
- Impact of “minor” CHD risk factors and residual risk
- Obesity and central adiposity in women
- Microcirculation and diabetes in women
- Impact of genetic background on metabolic profile and CVD risk in women
- Diet in diabetic women
- Psychosocial issues and adherence to treatment
Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ije/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ije/diacar/ according to the following timetable: