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Vitamin D Binding Protein and Vitamin D Levels

Call for Papers

Vitamin D deficiency is common in the general world population. Since circulating 25(OH) D levels vary among different ethnic populations, it is difficult to define vitamin D deficiency. Vitamin D binding protein (DBP) is the major transport protein for vitamin D metabolites in plasma, and 88–93% of 25(OH) D in the circulation is bound to DBP. Recent studies have found that serum DBP levels are decreased in type 1 diabetes, chronic liver, and renal diseases. It is unclear whether a change in levels of DBP would have any effect on concentrations of vitamin D metabolites, as DBP circulates at a higher level than its ligands. It is also unclear the etiology behind changes in DBP levels and its relationship to PTH and 25(OH) D levels.

We invite original research articles as well as review articles that seek to define the relationship of DBP and vitamin D levels in different disease conditions in human and animal models. We are interested in articles that explore free and bioavailable vitamin D levels, its relation to levels of vitamin D metabolites, and its association with risks of various diseases including cancer, osteoporosis, and diabetes. Potential topics include, but are not limited to:

  • DBP levels in various disease conditions
  • DBP levels in different ethnic populations
  • Genetic variations of DBP and vitamin D metabolites
  • Factors affecting free and bioavailable vitamin D levels
  • The role of DBP during growth and pregnancy
  • Associations of DBP and vitamin D levels with cancer, osteoporosis, diabetes, and other diseases

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ije/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ije/dbind/ according to the following timetable:

Manuscript DueFriday, 24 January 2014
First Round of ReviewsFriday, 18 April 2014
Publication DateFriday, 13 June 2014

Lead Guest Editor

  • Xiangbing Wang, Division of Endocrinology, Metabolism and Nutrition, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08093, USA

Guest Editors

  • Arthur Santora, Merck, Rahway, NJ 07065, USA
  • Sue A. Shapses, Department of Nutritional Sciences, Rutgers University, New Brunswick, NJ 08901, USA
  • Zhongjian Xie, Institute of Metabolism and Endocrinology, Central South University, Changsha, Hunan 410083, China