About this Journal Submit a Manuscript Table of Contents

Hyperglycemic Emergencies in Pediatric Diabetes

Call for Papers

Diabetic ketoacidosis (DKA) is a metabolic derangement often associated with a delayed diagnosis of the onset of type 1 diabetes or resulting from failure of insulin administration or delivery in a patient with established diabetes. Its worldwide frequency is extremely variable, mainly depending on geographical and socioeconomic factors: lower frequency in countries with a higher incidence of type 1 diabetes and more common in poorer countries. The epidemiology of type 1 diabetes in children and, therefore, of DKA is rapidly changing throughout the world, possibly due to unknown environmental factors. The global negative economic trend may be adversely impacting low income families, especially in countries that do not have universal access to healthcare resources.

If properly treated in experienced centres, most patients recover uneventfully from DKA; however, DKA remains an important cause of morbidity and mortality, and severe DKA may lead to cerebral edema, which is associated with high mortality and risk of permanent neurological injury. Several evidence-based diagnostic and therapeutic protocols have been published but are probably used predominantly in centers where there is high awareness of the condition and the healthcare system is good. Potential topics include, but are not limited to:

  • New insights into DKA pathogenesis and treatment
  • New insights into cerebral edema pathogenesis and treatment
  • Epidemiology of DKA in children with type 1 diabetes in various countries, including specific local aspects
  • Epidemiology of DKA in children and adolescents with type 2 diabetes
  • Evaluation and management of hyperglycemia hyperosmolar syndrome (HHS)
  • Management of DKA cases resistant to standard treatments and prone to cerebral edema
  • Variation in mortality rates for DKA and cerebral edema in various countries
  • Strategies to increase awareness of new onset of diabetes leading to early diagnosis and treatment in children
  • Economic burden of DKA and cerebral edema
  • Management protocols for centers with limited healthcare resources

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ije/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ije/pediab/ according to the following timetable:

Manuscript DueFriday, 7 March 2014
First Round of ReviewsFriday, 30 May 2014
Publication DateFriday, 25 July 2014

Lead Guest Editor

Guest Editors