Gene Duplication and the Genome Distribution of Sex-Biased Genes

Figure 3

Gene duplication to the Y, out of the X and neo-X chromosomes and between autosomes, often leads (with or without the loss of the parental gene) to sex-biased expression (often male tissue-specific expression; blue). Sex-biased expression (in blue) appears to evolve often as long as the duplication involves relocation. Both RNA-mediated and DNA-mediated gene duplication appear to contribute to these effects.