Comparative Analyses of Homocitrate Synthase Genes of Ascomycetous Yeasts

Figure 1

Phylogenetic relationships among 71 fungal homocitrate synthases. The phylogenetic tree was constructed based on multiple alignment with complete deletion of gap sites using the maximum likelihood method of MEGA software [10] with 100 bootstrap analyses. The WAG model was used as the amino acid substitution model. A total of 103 amino acid sites were considered. The γ-distributed rate was considered, and the number of discrete gamma categories was 3. The gamma was 0.81; the discrete rates were 0.14, 0.65, and 2.2.