Research Article

Sex-Biased Networks and Nodes of Sexually Antagonistic Conflict in Drosophila

Table 1

Characteristics of sex-biased and unbiased networks. Each of the sex-unbiased, male-, and female-biased networks are classified into subnetworks by the expression bias of the interacting nodes. The letter codes A, U, F, and M refer to the node types “All”, “Unbiased”, “Female-biased”, and “Male-biased”, respectively. The number of nodes and the number of edges refer to first letter (boldface) of the network type. For example, the pair X-Y refers to all nodes of type X that have an edge to a node of type Y. The summary statistics reported are: (1) the total number of nodes (of boldface type), (2) the total number of unique edges connecting those nodes, (3) the overall ratio of edges per node, computed by dividing the second column by the first column, (4) the mean number of edges per node, (5) the standard deviation in the number of edges per node about the mean, (6) the 25th percentile of the number of edges per node, (7) the 75th percentile of the number of edges per node, (8) the exponent of the best fit power law to the degree distribution, and (9) the degree lower limit cutoff for a node to be included in the power law fit. Reported values are for the strict DroID network that only include interactions based on physical, experimental evidence; values in parenthesis refer to the permissive network that include all evidence types in the DroID database version “2012_04”. The power law exponent is fit to the tail of the edges per node binned distribution (bin size = 5); edge per node values below the cutoff indicated in the last column are not used in the power law fit.

NetworkNodesEdgesEdges/nodesMean edges/nodeStD edges/node25th%75th%ExponentCutoff

A-A 12,453 (12,628) 237,954 (403,518) 19.1 (32.0) 38.1 (63.7) 235.0 (244.7) 6 (9) 31 (59) −2.77 (−2.13) 25 (25)

U-A 8,432 (8,517) 219,401 (370,642) 26.0 (43.5) 39.2 (65.6) 233.9 (244.1) 7 (11) 33 (61) −2.79 (−2.17) 25 (25)
U-U 8,302 (8,429) 124,730 (214,508) 15.0 (25.4) 36.6 (61.3) 219.9 (229.3) 6 (10) 30 (57) −2.80 (−2.19) 25 (25)
U-F 7,378 (7,680) 68,794 (108,317) 9.3 (14.1) 31.1 (51.6) 197.5 (206.0) 5 (7) 26 (47) −3.13 (−2.46) 5 (5)
U-M 6,024 (6,802) 25,877 (47,817) 4.3 (7.0) 27.3 (44.7) 183.5 (190.3) 3 (5) 24 (40) −2.61 (−2.66) 5 (5)

F-A 1,446 (1,452) 85,430 (137,027) 59.0 (94.4) 28.6 (46.7) 192.8 (199.4) 3 (5) 25 (41) −2.59 (−1.54) 25 (25)
F-U 1,430 (1,440) 68,794 (108,317) 48.1 (75.2) 29.2 (47.5) 196.5 (202.9) 3 (5) 25 (42) −2.67 (−1.73) 20 (20)
F-F 1,348 (1,365) 9,270 (16,956) 6.9 (12.4) 28.7 (46.9) 193.9 (200.3) 4 (5) 24 (41) −3.01 (−1.92) 10 (10)
F-M 1,127 (1,244) 7,366 (11,754) 6.5 (9.4) 28.2 (45.9) 191.7 (198.0) 3 (5) 24 (40) −2.09 (−2.23) 5 (5)

M-A 2,575 (2,659) 35,160 (63,737) 13.7 (24.0) 27.5 (44.9) 188.3 (194.7) 3 (4) 23 (39) −2.55 (−1.79) 15 (15)
M-U 2,423 (2,547) 25,877 (47,817) 10.7 (18.8) 26.7 (43.7) 184.8 (191.2) 3 (4) 23 (38) −2.83 (−1.98) 15 (15)
M-F 1,622 (1,832) 7,366 (11,754) 4.5 (6.4) 26.1 (42.5) 182.1 (188.2) 3 (4) 22 (37) −2.90 (−2.42) 5 (5)
M-M 1,327 (1,636) 1,917 (4,166) 1.4 (2.5) 25.5 (41.4) 180.0 (185.7) 3 (4) 22 (36) −2.75 (−2.18) 5 (5)