Conservation/Mutation in the Splice Sites of Cytokine Receptor Genes of Mouse and Human

Table 1

The cytokine receptors analyzed in this study. (1) is the immunoglobulin superfamily receptors; (2) is the class I cytokine receptor family; (3) is the class II cytokine receptor family (interferon receptor family); (4) is the tumor necrosis factor receptor superfamily; (5) is the chemokine receptor family; (6) is the transforming growth factor beta receptor family.

RECEPTOR (Receptor family) (Number of exons)
Interleukin 1 receptor, type I (IL1R1) (1) (10 exons)
C-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) (1) (21 exons)
Interleukin 2 receptor, alpha (IL2RA) (2) (8 exons)
Interleukin 2 receptor, beta (IL2RB) (2) (9 exons)
Interleukin 2 receptor, gamma (IL2RG) (2) (8 exons)
Interleukin 4 receptor (IL4R) (2) (9 exons)
Interleukin 13 receptor, alpha 1 (IL13RA1) (2) (11 exons)
Interleukin 13 receptor, alpha 2 (IL13RA2) (2) (9 exons)
Erythropoietin receptor (EPOR) (2) (8 exons)
Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (CSF2RB) (2) (13 exons)
Colony stimulating factor 3 receptor (granulocyte) (CSF3R) (2) (15 exons)
Leukemia inhibitory factor receptor alpha (LIFR) (2) (19 exons)
Prolactin receptor (PRLR) (2) (8 exons)
Oncostatin M receptor (OSMR) (2) (17 exons)
Interleukin 10 receptor, alpha (IL10RA) (3) (7 exons)
Interleukin 10 receptor, beta (IL10RB) (3) (7 exons)
Interferon (alpha, beta, and omega) receptor 1 (IFNAR1) (3) (11 exons)
CD27 molecule (CD27) (4) (6 exons)
CD40 molecule, TNF receptor superfamily member 5 (CD40) (4) (9 exons)
Lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR) (4) (10 exons)
Chemokine (C-C motif) receptor 7 (CCR7) (5) (3 exons)
Chemokine (C-C motif) receptor 9 (CCR9) (5) (2 exons)
Chemokine (C-C motif) receptor 10 (CCR10) (5) (2 exons)
Chemokine (C-X-C motif) receptor 4 (CXCR4) (5) (2 exons)
Chemokine (C-X-C motif) receptor 5 (CXCR5) (5) (2 exons)
Transforming growth factor, beta receptor III (TGFBR3) (6) (16 exons)