Conservation/Mutation in the Splice Sites of Cytokine Receptor Genes of Mouse and Human

Table 7

Conservation of groups of nucleotides (underlined) in the terminal hexanucleotides of the introns. Percentages are over the total of 216 couples of hexanucleotides.

Sequence	Random probability (%)	Actual (%)	Actual-expected (%)	𝑃
TTTxAG	3.45±2.68	8.80	5.35	<0.01
TTxTAG	4.31±2.98	9.26	4.95	<0.01
xTTTAG	1.69±1.89	4.63	2.94	<0.01
TxTTAG	1.48±1.77	4.17	2.69	<0.01
xTGCAG	2.27±2.19	5.09	2.82	0.01
TTxxAG	20.70±5.95	29.63	8.93	<0.01
xxTTAG	3.47±2.69	6.48	3.01	0.02
xTGxAG	4.50±3.05	8.33	3.83	<0.01