Evolution of the B-Block Binding Subunit of TFIIIC That Binds to the Internal Promoter for RNA Polymerase III

Figure 1

Four regions with conserved sequence similarities in the eukaryotic B-block binding subunits. The N-terminal region (shown as region I in the figure), near the N-terminal region (regions II and III), and near the C-terminal region (region IV) [10]. In the Pfam database, which is a large collection of protein families, the eukaryotic B-block binding subunits are shown to contain the specific HTH motif classified as the B-block_TFIIIC family (PF04182) (http://pfam.sanger.ac.uk/family/PF04182#tabview=tab0). The motif is in region II in most eukaryotic subunits. GI: 101943240 and GI: 75264084 are the numbers updated from GI: 4753161 and GI: 25402830, respectively [10].