Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes
Table 2
Eukaryotic SC proteins, their functional domains, and the total protein size (amino acid residues, aa).
SC central space proteins
LE proteins and other SC proteins
Protein
Functional domainsa
Total size, aa
Protein
Functional domainsa
Total size, aa
Zip1 Scb
Bacterial SMC, Smc, AAA_13
875
Hop1 Sc
HORMA
605
ZYP1a At
Two bacterial SMC domains
871
Red1 Sc
Rec10/Red1
827
ZYP1b At
Two bacterial SMC domains, PRK00409
856
Hop1 Sp, a linear element component
RING finger
528
C(3)G Dm
Two bacterial SMC domains
744
Rec10 Sp, a linear element component
Rec10/Red1
791
CORONA Dm
—
207
ASY1 At
HORMA, SWIRM
596
SYP-1 Ce
Smc
489
ASY2 At
HORMA
1399
SYP-2 Ce
—
213
C(2)M Dm
Rad21_Rec8_N cohesin domain
570
SYP-3 Ce
SGNH_plant_lipase_like
224
HIM-3 Ce
HORMA
291
SYP-4 Ce
—
605
SYCP2 Dr
—
995
SYCP1 Dr
SCP-1
537
SYCP3-like Dr
COR1
240
SYCE1-like Dr
—
206
SC65 Dr, a SC protein
Bacterial rpoC2_cyan
426
SYCE2 Dr
—
187
SYCP2 Mm
Bacterial COG4399
1500
TEX12 Af
—
135
SYCP3 Mm
COR1
254
SYCP1 Mm
SCP-1
993
SC65 Mm, a SC protein
—
443
SYCE1 Mm
Bacterial SMC
329
FKBP6 Mm, peptidyl-prolyl cis-trans isomerase
FKBP_C, TPR
327
SYCE2 Mm
—
177
SYCE3 Mm
—
88
TEX12 Mm
—
123
According to the CDART output.
bThe model organisms are designated as in Table 1. See protein IDs in Table 1. The SMC, Smc, SCP-1, COR1, and RAD21 domains are characteristic of structural chromosome proteins. The HORMA domain recognizes the chromatin state and facilitates the interactions with other proteins. PRK00409 is involved in recombination. Cis-trans isomerases catalyze the isomerization of protein molecules having double bonds. The other domains are not related to meiosis.