Improvement of Amperometric Biosensor Performance for H₂O₂ Detection based on Bimetallic PtM (M = Ru, Au, and Ir) Nanoparticles

Table 1

Comparison of the performance of various H₂O₂ sensors based on electrochemical measurement.

Catalyst	Sensitivity; (𝜇A·mM^−1·cm^−2)	% RSD	LOD; (𝜇M)	Applied potential versus Ag/AgCl (V)	References
Pt NPs	221.77	10.5	3.3	+0.25	This work
PtRu NPs	539.01	0.5	1.7	+0.25	This work
PtAu NPs	415.46	9.1	2.0	+0.25	This work
PtIr NPs	405.52	2.0	0.8	+0.25	This work
Hb/GNPs/Hb/MWNT	205.41	3.5	0.08	−0.3	[28]
Ag NPs/GO	13.93	3.9	1.9	−0.3	[29]
Pt/TiO2/CNT	0.85	5.5	4	+0.3	[30]
CNT/Pt NPs	1.8∗10^3	3.5	1.2	+0.55	[31]
MP-Pt-ME	2.8∗10^3	no	4.5	+0.6	[32]

NPs: nanoparticles, Hb: hemoglobin, GNPs: gold nanoparticles, MWNT: multiwall carbon nanotubes, GO: graphene oxide, MP: mesoporous, ME: microelectrode, CNT: carbon nanotube RSD: relative standard deviation, LOD: limit of detection, RSD of Hb/CNT/Au NPs: 𝑛=9 (0.1 mM H₂O₂), RSD of Ag NPs/GO: 𝑛=5 (1 mM H₂O₂), RSD of GC/CNT/Pt NPs: 𝑛=8 (1 mM), RSD of Pt/TiO₂/CNT: 𝑛=8 (0.2 mM H₂O₂), negative applied potential: reduction, and positive applied potential: oxidation.