Grape Seed Procyanidin Extract Improves Insulin Production but Enhances Bax Protein Expression in Cafeteria-Treated Male Rats

Table 3

Effects of GSPE treatment of cafeteria-fed rats on gene expression in the pancreas. **𝑃 ≤ 0.01 and ^#𝑃 ≤ 0.1 versus vehicle-treated group.

	Cafeteria + vehicle	Cafeteria + GSPE
Ins2	1.16 ± 0.3	0.55 ± 0.1^#
Cpe	1.04 ± 0.2	0.2 ± 0.1**
Bcl-2	1.12 ± 0.2	0.96 ± 0.3
Bax	1.13 ± 0.3	1.18 ± 0.2
Bcl-2/Bax	1.67 ± 0.4	0.95 ± 0.4
Ccnd2	1.15 ± 0.3	1.80 ± 0.3