The Progress on Genetic Analysis of Nasopharyngeal Carcinoma

Zhou, Xiaofeng; Cui, Jing; Macias, Virgilia; Kajdacsy-Balla, André A.; Ye, Hui; Wang, Jianguang; Rao, P. Nagesh

doi:https://doi.org/10.1155/2007/57513

International Journal of Genomics

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Review Article | Open Access

Volume 2007 | Article ID 057513 | https://doi.org/10.1155/2007/57513

The Progress on Genetic Analysis of Nasopharyngeal Carcinoma

Xiaofeng Zhou,^1,2Jing Cui,³Virgilia Macias,⁴André A. Kajdacsy-Balla,⁴Hui Ye,^1,5Jianguang Wang,⁶and P. Nagesh Rao⁷

Academic Editor: W. Zhang

Received20 Nov 2007

Accepted09 Dec 2007

Published21 Jan 2008

Abstract

Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is one of the most common cancers in Southeast Asia. Both genetic and environmental factors contribute to the tumorigenesis of NPC, most notably the consumption of certain salted food items and Epstein-Barr virus infection. This review will focus on the current progress of the genetic analysis of NPC (genetic susceptibilities and somatic alterations). We will review the current advances in genomic technologies and their shaping of the future direction of NPC research.

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Copyright © 2007 Xiaofeng Zhou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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