Research Article

Comparative Analyses of Transcriptional Profiles in Mouse Organs Using a Pneumonic Plague Model after Infection with Wild-Type Yersinia pestis CO92 and Its Braun Lipoprotein Mutant

Figure 1

Venn diagram showing the overlap of major functions of genes identified as significantly altered in the liver, spleen, and lung of mice infected with WT Y. pestis CO92. Functions were obtained using Ingenuity software, with genes identified at 12 hours or 48 hours in each tissue type analyzed separately. Fisher’s Exact Test was used as the scoring method for determining significance of overrepresented molecular functions and pathways.
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