Yer ID Gene Name Gene Symbol Function Δlpp /WT FC Cell envelope YPO2394 major outer membrane lipoprotein mlpA lpp gene—cell envelope−361.9 YPO1125 peptidoglycan-associated lipoprotein Pal excC Maintenance of cell envelope integrity −22.3 YPO0448 putative lipoprotein — Cell envelope −26 Genomic functions y2424 putative transposase — Mobile and extrachromosomal element functions −76.8 Y1119.1n replication protein A repA DNA replication, recombination, and repair −31.9 YPO1968 transposase for insertion sequence IS100 ypmt1 /y1093Mobile and extrachromosomal element functions −22.3 Metabolism YPO2705 conserved hypothetical protein — Fermentation −93.1 YPO2805 putative aldo/keto reductase — Central intermediary metabolism −20.3 YPO3387 conserved hypothetical protein — Nitrogen fixation −16.7 y1601 acetyl CoA carboxylase, carboxytransferase component, beta subunit accD Fatty acid and phospholipid metabolism −48.3 YPO1161 molybdopterin [mpt ] converting factor, subunit 1 chlM/chlA4 Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides −15.7 YPO1177 D-lactate dehydrogenase dld Fermentation −6.4 YPO3376 enolase eno Glycolysis/gluconeogenesis −127.7 y1362 IMP dehydrogenase guaB Purine salvage pathway −22 YPO2993 PTS system, phosphocarrier protein hpr Degradation of proteins, peptides, and glycopeptides −29.3 YPO2329 D-lactate dehydrogenase htpH/hslI Fermentation −7 YPO2300 fumarate and nitrate reduction regulatory protein nirR Regulation of metabolic functions −15.7 YPO1413 putative nicotinate phosphoribosyltransferase pncB Biosynthesis of cofactors, prosthetic groups, and carriers −51.7 YPO3521 inorganic pyrophosphatase ppa Central intermediary metabolism −44.1 YPO0915 ribose 5-phosphate isomerase A rpiA Pentose phosphate pathway −124.7 Protein synthesis and repair YPO0242 polypeptide deformylase fms Protein modification and repair −4.1 y0688 protein chain initiation factor IF-2 infB Translation −30.2 YPO3074 peptidyl-prolyl cis-trans isomerase B ppiB Protein folding and stabilization −405.1 YPO0233 30S ribosomal protein S4 ramA Protein synthesis −3.2 YPO3748 50S ribosomal protein L7/L12 rplL Protein synthesis −6.7 YPO0228 50S ribosomal protein L15 rplO Protein synthesis −11.4 YPO0225 50S ribosomal protein L18 rplR Protein synthesis −8.7 YPO0218 50S ribosomal protein L29 rpmC Protein synthesis −11.6 y0299 50S ribosomal subunit protein L31 rpmE Protein synthesis −15.1 Transport YPO2672 putative urea transporter — Transport and binding proteins −33.3 YPO3156 ATP-dependent Clp protease ATP-binding subunit ClpX lopC Carbohydrate transport −29.3 YPO1783 ferritin rsgA/ftn Iron transport −12.4 Type III Secretion System YPO2905 attachment invasion locus protein ail Invasion of eukaryotic cells; Type III Secretion System −3.3 YPCD1.67c putative protein-tyrosine phosphatase Yop effector yopH Type III secretion effector protein −100.7 YPCD1.71c putative targeted effector protein yopJ/yopP Type III secretion effector protein −68.2 FC YPCD1.72c putative targeted effector protein kinase ypkA Type III secretion effector protein −21.2 YPCD1.40 putative Yops secretion ATP synthase yscN Type III secretion system component −30.7 YPCD1.42 putative type III secretion protein yscP Type III secretion system component −66.9 Other functions y0223 cold shock-like protein cspI Response to cold shock −68.7 YPO1363 putative virulence factor — Pathogenesis −34.8 y0815 superoxide dismutase precursor (Cu-Zn) sodC Resistance to reactive oxygen species −18.2 Unknown functions various genes (y3398, YPO0130, 0198, 1087, 1560, 1996, 2153, 2854, and 3699)