Table 1: Average frequency of substitutions across the promoter and TF binding sites of the L1 5′ UTR.

RegionActive L1 elements (%)Dead L1 elements (%)All L1 elements in the human genome (%)

Sense promoter0.660.992.14
YY10.150.271.38
Runx30.000.260.53
SRY-10.000.490.81
Runx3 ASP0.290.260.86
SRY-20.000.000.41
5′ UTR overall0.530.781.62