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Comparative and Functional Genomics
Volume 2012 (2012), Article ID 258284, 12 pages
http://dx.doi.org/10.1155/2012/258284
Research Article

Repertoire of Protein Kinases Encoded in the Genome of Takifugu rubripes

1Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India
2Max Planck Institute for Intelligent Systems (Formerly Max Planck Institute for Metals Research), BioQuant BQ0038, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany
3German Cancer Research Center, BioQuant BQ0038, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany
4Department of Functional Genomics and Cancer and Department of Structural Biology and Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, Université de Strasbourg, 1 rue Laurent Fries, 67404 Illkirch Cedex, France
5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD Cambridge, UK

Received 27 November 2011; Revised 14 February 2012; Accepted 28 February 2012

Academic Editor: G. Pesole

Copyright © 2012 R. Rakshambikai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary data 1 provides a list of all the 519 protein kinase like sequences encoded in the fugu genome along with their subfamily distribution, domain combination and information on presence of transmembrane helices. Supplementary data 2 presents percentage-wise distribution of all the subfamilies of protein kinases encoded in fugu genome in comparison to other model organisms. Supplementary data 3 shows a dendrogram depicting clustering of kinases of Dual specificity tyrosine regulated kinases (DYRK) subfamily from fugu, human, yeast, Drosophila, C.elegans and Zebrafish. Supplementary data 4 gives the results of BLAST search, in SWISSPROT database, for each of fugu protein kinase sequences belonging to DYRK subfamily.

  1. Supplementary File1
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  4. Supplementary File4