Table 3: Biological pathways controlled by IR-modulated miRNAs and their association with ionizing radiation response.

Identified pathwaysNumber of miRNA target genesAssociation with IR responseReference

Adherens junction10Yes [42]
Aldosterone-regulated sodium reabsorption7UnknownN/A
Apoptosis9Yes [38]
Cell cycle12Yes [41]
Endocytosis20Yes [35]
Focal adhesion17Yes [43]
Insulin signaling19Yes [37]
Long-term potentiation11UnknownN/A
MAPK signaling22Yes [33]
Neutrotrophin signaling12UnknownN/A
Oocyte meiosis13Yes [44]
p53 signaling8Yes [39]
Regulation of actin cytoskeleton20Yes [34]
Renal cell carcinoma9Yes [45]
TGF-β signaling10Yes [40]
Thyroid cancer6Yes [46]
Ubiquitin-mediated proteolysis17Yes [47]