Features of Methylation and Gene Expression in the Promoter-Associated CpG Islands Using Human Methylome Data

Table 2

Pearson’s correlation coefficient between methylation level of promoter-associated CGIs and gene expression strength.

Method*	H1			IMR90
	𝑟	𝑃		𝑟	𝑃
TJ-CGIs	−0.016	0.128		−0.021	0.0419
CGCs-15	−0.037	4.78 × 10^−4		−0.036	7.52 × 10^−4
CGCs-20	−0.037	9.47 × 10^−4		−0.040	3.33 × 10^−4
UCSC-CGIs	−0.045	1.40 × 10^−5		−0.038	2.89 × 10^−4

*The methods/algorithms for screening CpG islands or CpG clusters are described in Section 2.