Feature Identification of Compensatory Gene Pairs without Sequence Homology in Yeast
Figure 3
The probability of transcriptional compensation and the score of the motif-content overlap. In this analysis, SSL pairs were considered to have functional compensation potential only if they were in the same functional module and had significant ratios of common neighbors. Furthermore, the logarithm of the transcriptional response to deletion of the counterpart member was at least 1.5 (). The number of qualified compensation—providing candidate pairs (log ratio ≥1.5) was divided by the total number of functionally characterized pairs (regardless of the log ratio) for each of the ranges of motif-overlapped ratios.
