Human Genomic Deletions Generated by SVA-Associated Events

Table 4

Types of repetitive sequences involved in the breakpoints of SRAD loci.

Locus	Left break point	Right break point
87	Unique sequence	SVA_B^(1)
273	L1MA5A	SVA_B^(2)
361	SVA_B^(2)	Unique
432	SVA2^(6)	Unique
574	SVA_A^(1)	L1PA5
689	SVA_C^(1)	ERVL-E-int
1505	SVA_D^(2)	Unique sequence
1652	AluJr4	SVA_C^(5)
2299	Simple repeat (TA)	SVA_D^(1)
2335	AluSx1	SVA_D^(3)
2493	SVA_A^(4)	SVA_A^(4)
2836	SVA_C^(1)	Unique
2981	SVA_A^(2)	AluSg4

Each number in the parenthesis indicates the localization of the break point in the SVA element (⁽¹⁾: Alu-like, ⁽²⁾: VNTR, ⁽³⁾: SINE-R, ⁽⁴⁾: poly-A tail, ⁽⁵⁾: hexamer repeats, and ⁽⁶⁾: DNA sequence specific to SVA2.)