Review Article

Turning on Myogenin in Muscle: A Paradigm for Understanding Mechanisms of Tissue-Specific Gene Expression

Figure 1

Conserved DNA binding elements within the Myog promoter. Conserved DNA binding elements within the proximal promoter (−184 to +33 bp) that have been characterized for a role in regulating Myog expression include: E-Box (E1 and E2—blue), Pbx element (orange), Mef3 (red), Mef2 (pink), and the TATA Box (green). Transcription factors that are known to bind at each of the elements in either proliferative or differentiation myoblasts are summarized.
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