Table 4: Phylogenetic comparison of human basal polyadenylation factors. Human basal polyadenylation factors were compared to homologous factors in other species by two criteria: percent length is the change in the number of amino acids as compared to the specific human polyadenylation factor. Positive identity is the percentage of amino acids that align to the human polyadenylation factor that are the same or similar to amino acids.

SpeciesHomolog% length% positive Identity

CPSF1MouseCPSF110098
ChickenLOC770075591
FlyCPSF160 iso. A10163
CPSF160 iso. B9861
MosquitoAGAP011340-PA9965
Purple sea urchinLOC5847738570
Trypanosome (T. cruzi)Tc00.1047053506871.14010041
Trypanosome (T. brucei)Tb11.01.617010041
NematodeCpsf-110152
RiceOs04g02522003057
Thale cressCPSF16010050
Wine grapeLOC10025670610049
Fission yeastCTF110046
Budding yeastCTF19444

CPSF2MouseCPSF210099
ChickenCPSF210097
FlyCPSF100 iso. A9769
CPSF100 iso. B8568
MosquitoAGAP002474-PA9571
Purple sea urchinLOC5820509975
Trypanosome (T. cruzi)Tc00.1047053504109.11010342
Trypanosome (T. brucei)Tb11.03.091010542
NematodeCPSF-210860
RiceOs09g05694009456
Thale cressCPSF1009557
Wine grapeLOC1002678659562
Fission yeastCFT210249
Budding yeastCFT211046
Archaea (H. volcanii)EPF18240

CPSF3MouseCPSF310099
ChickenCSPF310197
FlyCPSF7310079
MosquitoAGAP001224-PA8588
Purple sea urchinLOC5914552489
Trypanosome (T. cruzi)Tc00.1047053511003.2216378
Trypanosome (T. brucei)Tb927.4.134011373
NematodeCPSF-310375
RiceOs03g085290010272
Thale cressCPSF73-I10172
CPSF73-II9072
Wine grapeLOC10026104210172
Fission yeastYSH111367
Budding yeastYSH111460
ArchaeaEPF26045

CPSF4MouseCPSF48275
ChickenCPSF49088
FlyClp11064
MosquitoAGAP005735-PA29047
Purple sea urchinLOC76504610966
Trypanosome (T. cruzi)Tc00.1047053511555.4010148
Trypanosome (T. brucei)Tb11.01.460010348
NematodeCPSF-411262
RiceOs06g067770027364
Thale cressCPSF3010252
Wine grapeLOC10025325827567
Fission yeastYTH16372
Budding yeastYth1p7864

FIP1L1MouseFIP1L9892
ChickenFIP1L13088
FlyFIP111858
MosquitoAGAP001514-PA9663
Purple sea urchinLOC58016414260
Trypanosome (T. cruzi)Tc00.1047053507601.804860
Trypanosome (T. brucei)Tb927.5.43204765
NematodeF32D1.98679
RiceOs01g03775007358
Thale cressFIP1[V]20368
Wine grapeLOC10025196025189
Fission yeastSPAC22G7.105882
Budding yeastFip15552

CstF1MouseCstf110099
ChickenCstf112599
FlyCstF-50 isoform A9887
CstF-50 isoform B7465
MosquitoAGAP002776-PA9372
Purple sea urchinLOC5828549574
Trypanosome (T. cruzi)Tc00.1047053511365.1012142
Trypanosome (T. brucei)Tb10.61.057012043
Nematodecpf-110069
RiceOs03g075490010958
Thale cressAT5G6094010057
Wine grapeLOC10026723311357

CstF2MouseCSTF210196
ChickenCSTF28270
FlyCstF-647382
MosquitoAGAP010918-PA6881
Purple sea urchinLOC75985811875
Trypanosome (T. cruzi)Tc00.1047053506795.105962
Trypanosome (T. brucei)Tb927.7.37305963
Nematodecpf-26273
RiceOSs11g01761008855
Thale cressCSFF648047
Wine grapeLOC1002562969449
Fission yeastCFT16373
Budding yeastRNA155175

CstF2TMouseCSTF2t10393

CstF3MouseCstf310099
ChickenCstf310099
Flysu(f)10274
MosquitoAGAP003019-PA71075
Purple sea urchinLOC5919397887
LOC5828999074
NematodeSuf-110368
RiceOs12g057190070971
Thale cressCSTF7771371
Wine grapeLOC10026203374769
Fission yeastRNA1410252
Budding yeastRNA149449

CPSF6MouseCPSF610099
ChickenCPSF610098
FlyCG718511894
MosquitoAGAP005062-PA11764
Purple sea urchinLOC57732616362
NematodeD1046.18943
RiceOs09g047510011060
Thale cressAT5G5567010650
Wine grapeLOC10026814111651

CPSF7MouseCPSF710099
ChickenCPSF79892
Thale cressAT1G1319012246

NUDT21MouseNUDT2110099
ChickenAMFR33699
FlyCG3689 isoform B8983
CG3689 isoform C10485
MosquitoAGAP007242-PA10286
Purple sea urchinLOC57971610096
Trypanosome (T. cruzi)Tc00.1047053509509.4012951
Tc00.1047053508207.22012951
Trypanosome (T. brucei)Tb927.7.162013249
NematodeF43G9.510084
RiceOs04g068310011473
Thale cressAT4G255508873
CFIM-259867
Wine grapeLOC100261950 isoform 18873
LOC100261950 isoform 29270

Clp1MouseClp110099
ChickenClp110098
Flycbc9975
MosquitoAGAP007701-PA11765
Purple sea urchinLOC7635818570
Trypanosome (T. cruzi)Tc00.1047053507027.599747
Tc00.1047053506941.2299747
Trypanosome (T. brucei)Tb927.6.369010043
NematodeF59A2.410168
RiceOs02g021750012058
Thale cressCLPS511846
CLPS312360
Wine grapeLOC10024238011860
Fission yeastSPAC22H10.05c10854
Budding yeastClp10447

PCF11MousePCF1110097
ChickenPCF119777
FlyPCF1112659
MosquitoAGAP001271-PA12056
Purple sea urchinLOC58241417064
NematodeR144.25352
RiceOs09g05661006958
Thale cressPCFS45254
Wine grapeLOC1002510897055
Fission yeastSPAC4G9.04c4165
Budding yeastPCF114056

WDR33MouseWDR3310096
ChickenWDR339888
FlyCG11096080
MosquitoAGAP001362-PA27174
Purple sea urchinLOC5747938682
Trypanosome (T. cruzi)Tc00.1047053511491.1403353
Trypanosome (T. brucei)Tb927.6.18303352
NematodeR06A4.96157
RiceOs04g059980015547
Thale cressFY19865
Wine grapeLOC10026356723770
Fission yeastPFS23864
Budding yeastPFS23558

RBBP6MouseRBBP610093
ChickenRBBP610182
FlySNAMA6959
MosquitoAGAP011217-PA6960
Purple sea urchinLOC5841973663
NematodeTAG-2146351
RiceOs10g04310002648
Thale cressAT5G474305047
Wine grapeLOC10025257110162
Fission yeastSPBP8B7.15c2751
Budding yeastMPE12549

PPP1CAMousePPP1CA100100
ChickenPPP1CC9894
FlyPP1alpha-96A9992
MosquitoAGAP011166-PA9690
Purple sea urchinLOC58614210094
Trypanosome (T. cruzi)Tc00.1047053508815.1109289
Trypanosome (T. brucei)Tb11.01.04509290
NematodeGSP-210095
RiceOS03g02680009589
Thale cressTOPP79484
Wine grapeLOC1002569949486
Fission yeastDIS29994
Budding yeastGLC79594

PPP1CBMousePPP1CB100100
ChickenPPP1CB100100
FlyPP1Alpha-96A10093
MosquitoAGAP003114-PA9793
Purple sea urchinLOC7523389997
Trypanosome (T. cruzi)Tc00.1047053508815.1109188
Trypanosome (T. brucei)Tb11.01.04509189
NematodeGSP-110097
RiceOs06g01641009892
Thale cressTOPP49890
Wine grapeLOC10025864910489
Fission yeastDIS210093
Budding yeastGLC79491