Research Article
A Complex Network of MicroRNAs Expressed in Brain and Genes Associated with Amyotrophic Lateral Sclerosis
Table 1
Multiplicity and cooperativity for all miRNAs.
| S. no. | Gene name | hsa-miR-370 | hsa-miR-874 | hsa-miR-423-3p | hsa-miR-323-5p | hsa-miR-760 | hsa-miR-149 | hsa-miR-139-3p | hsa-miR-744 | hsa-miR-324-3p | hsa-miR-339-3p | hsa-miR-654-5p | Total |
| 1 |
ALS2 | 1 | 1 | 1 | 1 | 1 | 2 | — | 1 | 1 | — | — | 9 | 2 |
APAF1 | 1 | 1 | 1 | — | 3 | 1 | 2 | — | — | — | 1 | 10 | 3 |
BAD | 4 | 1 | 2 | — | 2 | 3 | 3 | 3 | 1 | — | — | 19 | 4 |
BAX | 1 | 1 | 3 | 1 | 3 | 1 | 1 | — | — | 1 | 1 | 13 | 5 |
BCL2 | 1 | 1 | — | 1 | 1 | 1 | 2 | 1 | — | 1 | 2 | 11 | 6 |
BCL2L1 | 1 | 3 | — | — | — | — | 1 | 1 | — | — | 1 | 7 | 7 |
BID | 2 | 1 | 1 | 2 | — | 1 | — | 3 | 1 | — | — | 11 | 8 |
CASP1 | — | — | — | — | 1 | — | — | — | 1 | — | — | 2 | 9 |
GRIA1 | 1 | 1 | 1 | — | 1 | 2 | — | — | 1 | — | 1 | 8 | 10 |
GPX1 | — | 3 | 2 | 2 | 1 | — | — | 1 | — | 2 | — | 11 | 11 |
DERL1 | — | 1 | 1 | — | — | 1 | — | — | 1 | — | 1 | 4 | 12 |
DAXX | 1 | 2 | — | — | 2 | — | — | — | 1 | — | 3 | 9 | 13 |
CYCS | 3 | 2 | 2 | 1 | — | 2 | — | — | 1 | 1 | — | 12 | 14 |
CHP | 3 | — | — | 1 | — | 1 | 1 | — | — | — | — | 6 | 15 |
CCS | — | 3 | — | — | — | 4 | 1 | — | 1 | — | 1 | 10 | 16 |
CAT | 1 | 1 | 1 | 1 | 1 | 1 | — | — | — | — | — | 6 | 17 |
CASP9 | 1 | 3 | 2 | 2 | 1 | — | — | — | 1 | 1 | — | 11 | 18 |
CASP3 | 1 | 1 | — | 1 | 1 | 1 | — | — | — | — | — | 5 | 19 |
TOMM40 | 4 | 3 | 2 | 2 | 3 | 1 | 2 | 1 | 1 | — | 1 | 20 | 20 |
TNFRSF1A | 5 | 2 | 4 | 4 | 1 | 1 | 1 | — | 2 | 1 | 1 | 22 | 21 |
TNF | 1 | 2 | — | — | 2 | — | 1 | — | — | 1 | — | 7 | 22 |
SOD2 | — | — | — | — | — | — | — | — | — | — | — | 0 | 23 |
SLC1A2 | 3 | 1 | 3 | 1 | 1 | 1 | — | 2 | 1 | 2 | 1 | 16 | 24 |
RAC1 | 4 | — | — | — | 1 | — | — | 1 | — | 1 | — | 7 | 25 |
RAB5A | 1 | — | 2 | 1 | — | 1 | — | 2 | — | 1 | 1 | 9 | 26 |
p53 | 1 | 1 | 1 | 1 | 1 | — | 2 | 2 | — | 1 | 1 | 11 | 27 |
NOS1 | 2 | 1 | 3 | 3 | 2 | 2 | 2 | 1 | — | — | 1 | 17 | 28 |
NEFM | 3 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | — | 1 | 16 | 29 |
NEFL | 3 | 1 | 4 | 1 | 1 | — | 1 | — | 1 | 1 | — | 13 | 30 |
NEFH | 3 | 1 | 2 | 2 | 2 | — | — | — | 1 | 2 | 1 | 14 | 31 |
MAPK14 | 4 | 3 | 3 | 4 | 1 | 1 | — | — | — | — | — | 16 | 32 |
MAP3K5 | 2 | 3 | 1 | 5 | 2 | 2 | — | — | — | 2 | — | 17 | 33 |
MAP2K6 | 2 | — | — | — | 1 | — | — | 1 | — | — | — | 4 | 34 |
MAP2K3 | 2 | 4 | — | 3 | 2 | 1 | 1 | — | 1 | 1 | 1 | 16 | 35 |
PRPH | 3 | 2 | 2 | 2 | 1 | 4 | 2 | 1 | 3 | 2 | 1 | 23 |
| Total | | 65 | 52 | 45 | 44 | 41 | 36 | 25 | 22 | 21 | 21 | 21 | 392 |
|
|