Global Alignment of Pairwise Protein Interaction Networks for Maximal Common Conserved Patterns

Table 1

A summary of classification of different network alignment tools.

Tools	Local	Global	Pairwise	Guided models
PathBLAST	×		×	Evolution
NetworkBLAST	×			Evolution
NetworkBLAST-M	×			Evolution
MaWish	×		×	Duplication/divergence
Graemlin 1.0	×			General evolution
Graemlin 2.0		×		Evolution, duplication, and so forth
Isorank		×	×	Evolution
Isorank-M		×		Evolution
HopeMap		×	×	Evolution, function

Note*. For multiple alignment of HopeMap, only results of yeast/fly/worm are provided in this paper. We are preparing more results in ongoing research. In HopeMap, the global alignment concept is same as in Isorank and Graemlin 2.0.