A Mechanistic, Stochastic Model Helps Understand Multiple Sclerosis Course and Pathogenesis
Figure 2
Time evolution of health and no health states for three sample patients taken from the set of 70 patients. The health state of each patient has been represented by a sequence of plus one (+1) and minus one (−1) corresponding to the states of relapses and remissions, respectively. Events are reported on a weekly scale and the shift to a secondary progressive form of the disease has been excluded.