Research Article

γ-H2AX: A Novel Prognostic Marker in a Prognosis Prediction Model of Patients with Early Operable Non-Small Cell Lung Cancer

Table 1

Characteristics of the prediction variables.

VariablesNo. of patientsPercentage (%)

Total number of patients96
Age (years)
 Mean SD
653637.5
 ≥656062.5
Gender
 Male7780.2
 Female1919.8
Histology
 Adenocarcinoma4243.8
 Squamous cell carcinoma4243.8
 Large cell carcinoma88.3
 Undifferentiated carcinoma44.1
T status
 T11313.5
 T26567.7
 T31818.8
Regional lymph node status (N)
 N05052.1
 N12728.1
 N21919.8
Stage
 I4142.7
 II2222.9
 III3132.3
 IV22.1
Grade
 Low2526
 Medium/high7174
Border of bronchus
 Positive1212.5
 Negative8487.5

FEV1 70%1717.7
Positive vessel infiltration 4142.7
Positive lymphatic infiltration 2121.9
Positive pleural infiltration 4647.9
Chemotherapy adjuvant 7275.0
Radiotherapy adjuvant 4142.7
High expression of P53 5557.3
High expression of caspase 32425.0
High expression of -H2AX 2526.0
High expression of Ki67 2930.2