MicroRNAs in the Neural Retina

Table 2

Differentially expressed microRNAs in retinal cell types.

MicroRNA	Regulation/function	Retinal cell type	Refs
miR-204, miR-211	Upregulated	RPE	[48]
miR-23a	Upregulated (in healthy cells); Downregulated (in AMD)	RPE	[49]
miR-183/96/182	Downregulated in dark; Upregulated in light	Photoreceptors and interneurons of the inner nuclear layer	[36]
miR-29b	Upregulated after streptozotocin (STZ) injection; upregulation protects against apoptosis	RGCs and cells of the INL	[47]
mir-133b	Overexpression suppresses maturation and function of dopaminergic amacrine cells	Dopaminergic amacrine cells	[46]
mir-124	Abundantly expressed in differentiated neurons	All retinal cell layers, but is not detected in the RPE	[45]
miR-155*, miR-124.	Resting microglia: low expression of miR-155 and high expression of miR-124; Activation phenotype (M1): downregulation of miR-124, upregulation of miR-155; Activation phenotype (M2): upregulation of miR-124,; downregulation of miR-155	Microglia	[52]

∗Expression of these miRNAs has been reported for microglia of the brain.