Research Article

A Promoter Region Polymorphism in PDCD-1 Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China

Table 1

Characteristics of RA patients and controls.

CharacteristicRA patientsControls value

Total number 320309
Female248 (77.5)240 (77.7)>0.05a
Male72 (22.5)69 (22.3)
Age, mean SD years >0.05b
Duration of disease, years
RF+c261 (81.6)
RF−c59 (19.4)
Anti-CCP+c244 (76.4)
Anti-CCP−c76 (23.6)

Values are numbers (%); RA: rheumatoid arthritis; RF: rheumatoid factor; anti-CCP: anticyclic citrullinated peptide.
value calculated by Pearson chi-square test (all frequency >0.05) or Fisher’s exact test (any frequency <0.05).
b value calculated by Student’s -test.
cClinical data were not available for some cases.