Research Article
A Promoter Region Polymorphism in PDCD-1 Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China
Table 3
The association analysis of rs36084323 with RA (adjusted by sex) by using logistic regression.
| Model | Genotype | Cases (%) | Controls (%) | OR (95% CI) | value | AIC | BIC |
| Codominant | A/A | 24.7 | 31.1 | 1 | 0.049* | 871.3 | 884.6 | A/G | 45.1 | 46.5 | 1.22 (0.84–1.78) | G/G | 30.3 | 22.5 | 1.70 (1.11–2.61) |
| Dominant | A/A | 24.7 | 31.1 | 1 | 0.073 | 872.1 | 881 | A/G-G/G | 75.3 | 68.9 | 1.38 (0.97–1.96) |
| Recessive | A/A-A/G | 69.7 | 77.5 | 1 | 0.026* | 870.3 | 879.2 | G/G | 30.3 | 22.5 | 1.50 (1.05–2.14) |
| Overdominant | A/A-G/G | 54.9 | 53.5 | 1 | 0.73 | 875.2 | 884 | A/G | 45.1 | 46.5 | 0.95 (0.69–1.29) |
| Log-additive | — | — | — | 1.30 (1.05–1.61) | 0.015* | 869.4 | 878.3 |
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OR: odds ratio; 95% CI: 95% confidence intervals; AIC: Akaike’s information criterion; BIC: Bayesian information criterion; .
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