Research Article

In Silico Prediction of T and B Cell Epitopes of Der f 25 in Dermatophagoides farinae

Table 3

The results of B and T cell epitopes predictions.

ToolsLocation of the prediction results

B cell epitope predictionDNAStar protean11–19, 28–35, 68–77, 95–111, 130–139, 173–187, 193–197, 211–225.
BPAP20–26, 32–52, 54–70, 86–93, 138–168, 175–209, 218–242.
BepiPred 11–18, 30–34, 71–78, 99–107, 132–138, 168–183, 194–199, 210–224.

T cell epitope prediction (HLA-DR)DRB1*01:015–13, 11–19, 10–18, 13–21, 24–32, 26–34, 39–47, 46–54, 50–58, 53–61, 57–65, 58–66, 60–68, 66–74, 73–81, 82–90, 89–97, 90–98, 104–112, 107–115, 114–122, 119–127, 122–130, 143–151, 142–150, 156–164, 157–165, 161–169, 163–171, 167–175, 187–195, 190–198, 191–199, 195–203, 197–205, 203–211, 205–213, 227–235, 228–236, 232–240, 235–243, 239–247.
DRB3*01:0153–61, 66–74, 81–89, 191–199.
DRB4*01:0126–34, 38–46, 46–54, 48–56, 50–58, 107–115, 142–150, 158–166, 160–168, 238–246, 239–247.
DRB5*01:015–13, 11–19, 13–21, 20–28, 24–32, 26–34, 39–47, 46–54, 59–67, 66–74, 73–81, 89–97, 90–98, 143–151, 146–154, 150–158, 163–171, 165–173, 166–174, 203–211, 228–236, 238–246, 239–247.

T cell epitope prediction (HLA-DQ)HLA-DQA10101-DQB10501153–161, 154–162, 159–167, 160–168.
HLA-DQA10102-DQB10602 33–41, 40–48, 42–50, 57–65, 77–85, 117–125, 154–162, 192–200, 206–214, 213–221, 230–238, 237–245.
HLA-DQA10501-DQB1020119–27, 39–47, 37–45, 82–90, 100–108, 112–120, 122–130, 126–134, 158–166, 195–203, 220–228.
HLA-DQA10501-DQB103016–14, 34–42, 38–46, 39–47, 58–66, 66–74, 69–77, 72–80, 74–82, 77–85, 82–90, 85–93, 107–115, 117–125, 121–129, 133–141, 161–169, 166–174, 167–175, 169–177, 172–180, 192–200, 195–203, 203–211, 205–213, 206–214, 207–215, 213–221, 215–233, 228–236, 230–238, 232–240, 237–245.