Genetic Variations of Cytokines and Cytokine Receptors in Psoriasis Patients from China

Table 3

Correlation of psoriasis symptoms with SNPs in the IL genes.

SNP	Genotype	Psoriasis	Controls	OR (95% CI)	Allele	Psoriasis	Controls	OR (95% CI)
rs2243250	TT	127	189		T	315	476
	TC	61	98	0.93 (0.63–1.37)	C	85	120	1.07 (0.78–1.46)
	CC	12	11	1.62 (0.69–3.78)
	TC-CC	73	109	1.00 (0.69–1.45)
rs1800872	AA	93	138		A	272	399
	AC	86	123	1.04 (0.71–1.52)	C	128	197	0.95 (0.72–1.25)
	CC	21	37	0.84 (0.46–1.53)
	AC-CC	107	160	0.99 (0.69–1.42)
rs3212227	CC	19	51		C	142	230
	AC	104	128	2.18 (1.21–3.92)	A	258	366	1.14 (0.88–1.48)
	AA	77	119	1.71 (0.96–3.17)
	AC-AA	181	247	1.97 (1.12–3.45)
rs1800925	CC	140	222		C	332	516
	CT	52	72	1.15 (0.76–1.74)	T	68	80	1.32 (0.93–1.86)
	TT	8	4	3.17 (0.94–10.72)
	CT-CC	60	76	1.25 (0.84–1.86)
rs20541	CC	100	146		C	280	418
	CT	80	126	0.93 (0.64–1.36)	T	120	178	1.01 (0.77–1.33)
	TT	20	26	1.12 (0.59–2.12)
	CT-TT	100	152	0.96 (0.67–1.37)
rs56245420	AA	78	139		A	253	413
	AT	97	135	1.28 (0.87–1.87)	T	147	183	1.28 (1.00–1.71)
	TT	25	24	1.85 (0.99–3.46)
	AT-TT	122	159	1.36 (0.94–1.96)