Lack of Association of the Polymorphisms IL-17A (−197G/A) and IL-17F (+7488A/G) with Multibacillary Leprosy in Mexican Patients

Table 1

Allelic and gene frequencies of polymorphisms in IL-17A and IL-17F genes in patients with multibacillary leprosy and healthy controls.

	MB patients	CS	OR (95% CI)	value
	(%)	(%)
Genotype
IL-17A −197
GG	38 (56)	29 (42)	—	—
GA	30 (44)	40 (58)	0.57 (0.27–1.19)	2.11
AA	0 (0)	0 (0)
GA + AA	30 (44)	40 (58)	0.57 (0.27–1.19)	2.11
IL-17F +7488
AA	58 (82)	52 (76)	—	—
AG	13 (18)	16 (24)	0.73 (0.30–1.7)	0.58
GG	0 (0)	0 (0)
AG + GG	13 (18)	16 (24)	0.73 (0.30–1.7)	0.58
Allele
IL-17A −197
G	106 (78)	98 (71)	—	—
A	30 (22)	40 (29)	0.96 (0.39–1.24)	0.24
IL-17F +7488
A	129 (91)	120 (88)	—	—
G	13 (9)	16 (12)	0.76 (0.33–1.74)	0.60

The values are presented as frequency in percentage (%) and number () of genotypes or alleles. The frequencies comparison between groups was analyzed by Chi-square test. Statistical significance was at Yates corrected. OR, odds ratio; CI, confidence interval; , number of individuals; MB, multibacillary leprosy; CS, healthy controls.