Exploring the Functional Disorder and Corresponding Key Transcription Factors in Intraductal Papillary Mucinous Neoplasms Progression

Table 2

The TFs and target genes in different clusters.

Cluster	TF	Target genes	value
C1	FLI1	ANPEP, PDGFRB, SLA, ERG, PDGFC, MMP2, CCND2	0.0041
	ERG	ANPEP, CDH5, ESR1, FLT1, MMP2, VIM, VWF	0.0372
	ESR1	CXCL12, IGF1, ANGPTL4, APOE, ERG, SOCS2, CYP1B1, CAV1, EGF, PNRC1, PGR, FBLN1, SERPINE1	0.0451
	NFIC	VWF, COL18A1, ELN, IL6, TFPI2, ADA, RGN, SERPINE1, RBP1, F13A1	0.1671
	PGR	ALB, EGF	0.3925
	CEBPD	ELN, IL6	0.5027
	AR	IL6, PNRC1	0.4326
	CREM	FHL5, PLN	0.5806
C3	PPARG	CASP3, ADAM28	0.3851
	PPARA	HMGCS1	0.7016
C5	MYC	NFIL3	0.8412
C7	SP1	ABCG1, CYP3A4, KRT19	0.2409
	STAT1	IRF7	0.6291
	SMAD3	BCL2L1	0.4531