Research Article

Human Genes Encoding Transcription Factors and Chromatin-Modifying Proteins Have Low Levels of Promoter Polymorphism: A Study of 1000 Genomes Project Data

Table 1

Sequence sets used in analysis. The column “number of transcripts/genes” presents the count of transcripts that were computed after intersection of the respective subset with the whole-genome dataset of 47,469/18,817 transcripts/genes.

Dataset of transcriptsNumber of transcripts/genes
Full nameShort name

All protein-coding transcripts from the human genomeWhole-genome47,469/18,817

All transcription factors from TFClassAll TFs3,957/1,454

Transcription factors with zinc-coordinating DBDs (Superclass 2 from TFClass) ZNF2,074/750

Helix-turn-helix transcription factor genes (Superclass 3 from TFClass)HTH921/383

Basic domain transcription factor genes (Superclass 1 from TFClass)Basic432/170

Genes encoding transcription factors with DBDs of all other types (Superclasses 0, 4, 5, 6, 7, 8, and 9 from TFClass)Other554/160

Genes encoding chromatin-modifying proteins (according to GO, CREMOFAC, and CR Cistrome)Chr_Mod533/167

Genes encoding proteins involved in spermatogenesis (according to GO)Sperm936/361