Human Genes Encoding Transcription Factors and Chromatin-Modifying Proteins Have Low Levels of Promoter Polymorphism: A Study of 1000 Genomes Project Data
Table 1
Sequence sets used in analysis. The column “number of transcripts/genes” presents the count of transcripts that were computed after intersection of the respective subset with the whole-genome dataset of 47,469/18,817 transcripts/genes.
Dataset of transcripts
Number of transcripts/genes
Full name
Short name
All protein-coding transcripts from the human genome
Whole-genome
47,469/18,817
All transcription factors from TFClass
All TFs
3,957/1,454
Transcription factors with zinc-coordinating DBDs (Superclass 2 from TFClass)
ZNF
2,074/750
Helix-turn-helix transcription factor genes (Superclass 3 from TFClass)
HTH
921/383
Basic domain transcription factor genes (Superclass 1 from TFClass)
Basic
432/170
Genes encoding transcription factors with DBDs of all other types (Superclasses 0, 4, 5, 6, 7, 8, and 9 from TFClass)
Other
554/160
Genes encoding chromatin-modifying proteins (according to GO, CREMOFAC, and CR Cistrome)
Chr_Mod
533/167
Genes encoding proteins involved in spermatogenesis (according to GO)